A report on preparation, expansion and future outlook of COVID-19 testing in Gambia

Accepted: 16 May 2022
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Background: The outbreak of COVID-19 disease and rapid spread of the virus outside China led to its declaration as a Public Health Emergency of International Concern (PHEIC) in January 2020. Key elements of the early intervention strategy focused on laboratory diagnosis and screening at points of entry and imposition of restrictions in crossborder activities.
Objective: We report the role the Medical Research Council Unit, The Gambia (MRCG) played in the early implementation of molecular testing for COVID-19 in The Gambia as part of the national outbreak response.
Methods: Laboratory staff members, with experience in molecular biology assays, were identified and trained on COVID-19 testing at the Africa CDC training workshop in Dakar, Senegal. Thereafter risks assessments, drafting of standard operating procedures (SOPs) and inhouse training enabled commencement of testing using commercial RTPCR kits. Subsequently, testing was expanded to the National Public Health Laboratroy and also implemented across field sites for rapid response across the country.
Results: Capacity for COVID-19 testing at MRCG was developed and can process aproximately 350 tests per day, which can be further scaled up as the demand for testing increases.
Conclusion: The long presence of the Unit in The Gambia and strong collaborative relationship with the National Health Ministry, allowed for a synergistc approach in mounting an effective response that contributed in delaying the establishment of community transmission in the country.
Coronavirus (COVID-19) events as they happen [Internet]. [cited 2020 May 18]. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/events-as-they-happen
WHO | Pneumonia of unknown cause – China [Internet]. WHO. World Health Organization; [cited 2020 May 18]. Available from: http://www.who.int/csr/don/05-january-2020-pneumonia-of-unkown-cause-china/en/
2019 Novel Coronavirus (2019‑nCoV): STRATEGIC PREPAREDNESS AND RESPONSE PLAN [Internet]. [cited 2020 May 18]. Available from: https://www.who.int/docs/default-source/coronaviruse/srp-04022020.pdf
Hopman J, Allegranzi B, Mehtar S. Managing COVID-19 in Low- and Middle-Income Countries. JAMA. 2020 Apr 28;323(16):1549–50.
Udugama B, Kadhiresan P, Kozlowski HN, Malekjahani A, Osborne M, Li VYC, et al. Diagnosing COVID-19: The Disease and Tools for Detection. ACS Nano [Internet]. 2020 Mar 30 [cited 2020 May 23]; Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144809/
38194-doc-africacdc_covidbrief_03mar20_en.pdf [Internet]. [cited 2020 May 18]. Available from: https://au.int/sites/default/files/documents/38194-doc-africacdc_covidbrief_03mar20_en.pdf
Jarju S, Greenhalgh K, Wathuo M, Banda M, Camara B, Mendy S, et al. Viral Etiology, Clinical Features and Antibiotic Use in Children <5 Years of Age in the Gambia Presenting With Influenza-like Illness. Pediatr Infect Dis J. 2020 May 20;
guidance-and-sop-covid-19-virus-testing-in-nhs-laboratories-v1.pdf [Internet]. [cited 2020 May 18]. Available from: https://www.england.nhs.uk/coronavirus/wp-content/uploads/sites/52/2020/03/guidance-and-sop-covid-19-virus-testing-in-nhs-laboratories-v1.pdf
WHO. WHO | Personal protective equipment for COVID-19 [Internet]. WHO. World Health Organization; [cited 2020 Jun 2]. Available from: http://www.who.int/medical_devices/priority/COVID_19_PPE/en/
whoemc973.pdf [Internet]. [cited 2020 Aug 1]. Available from: https://www.who.int/csr/resources/publications/biosafety/whoemc973.pdf?ua=1
Quick J. nCoV-2019 sequencing protocol V.1 [Internet]. Protocols.io. 2020 [cited 2022 May 16]. Available from: https://www.protocols.io/view/ncov-2019-sequencing-protocol-bp2l6n26rgqe/v1?version_warning=no&step=7
Final_Sitrep-21st-22nd-March-2020.pdf [Internet]. [cited 2020 Aug 1]. Available from: http://www.moh.gov.gm/wp-content/uploads/2020/03/Final_Sitrep-21st-22nd-March-2020.pdf
Gambia_The_COVID-19_Sitrep-27-August-2020.pdf [Internet]. [cited 2020 Aug 30]. Available from: http://www.moh.gov.gm/wp-content/uploads/2020/08/Gambia_The_COVID-19_Sitrep-27-August-2020.pdf
Copyright (c) 2022 Ousman Secka, Eniyou C. Oriero, Sheikh Jarju, Aminata Vilane, Natalie Hofmann, Mamadou Ousmane Ndiath, Davis Nwakanma

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.